Join Our Research Laboratory in Singapore for an exciting journey to set up the Imaging Mass spectrometry (MS) capabilities within the Target & Pathway Biology group. As  a Senior Scientist, you will focus on developing imaging MS and LC-MS based workflows to support drug discovery pipelines by facilitating decision making based on distribution of proteins, lipids, metabolites, and candidate drugs. Utilizing state of the art  Mass spectrometry platforms within the site, you will be responsible for the application and development of the mass spectrometry technology to understand novel biological regulatory mechanisms, identify disease and pharmacodynamic biomarkers. You will work  closely with other scientists and will coordinate and integrate collaborative projects with the company scientists as well as with academic and clinical investigators in Singapore. You should have excellent background and track record in Mass spectrometry  and diverse interests in systems biology.

​What will you do:

• Subject matter expert in mass spectrometry-based platforms and able to provide scientific and technical expertise in the development and application of imaging-MS workflows to support drug discovery pipelines.

• Implement generation, integration, and interpretation of spatial multi-omics and LC-MS datasets (Metabolomics, Lipidomic and Proteomics) as part of a multi-modal approach to drive pipeline decisions. Perform analytical validation and develop QC practices.

• Operate, troubleshoot, and maintain high resolution and triple quadrupole mass spectrometry instrumentation.

• Analyse and interpret data with relevant vendor software and bioinformatics tools and integrate spatial multi-omics IMS datasets as part of a multi-modal approach to measure spatial biology, contextualize drug distribution and identify novel disease biomarkers.

• Continuously optimize and improve the Imaging mass spectrometry platform to support scientific or business processes, seeks opportunities and provides recommendations to enhance capability and support to improve safety, quality, speed, efficiency, and costs.

• Work collaboratively on company’s research projects with matrix teams within the department and other cross functional teams. Proactively pre-empt and respond to emerging project needs to align with business and departmental strategy.

• Identify, evaluate, and recommend innovative analytical technologies and emerging Imaging-MS platforms or capital investment opportunities to maximize the group efficiency and meet scientific objectives.

• Cross-train other scientists in Imaging-MS and LC-MS based proteomics or metabolomics techniques to ensure technical redundancy for these critical workflows in the department

• Operate with high level of autonomy in planning and executing experimentation, creation of research project proposals, reports, publications and other scientific communications related to research activities.

• Ensure reliable documentation of experiments and results in electronic notebooks and other documents in compliance with company policies and project needs.

• Sustain visibility, both inside and outside of disease or functional area by researching and presenting complex ideas and data.

• Proactively plan and execute own career development strategy that advances technical and functional knowledge to design experiments/projects that contribute to overall direction of department/discipline.

• Demonstrate consistent leadership behaviours. Ensure all activities comply with appropriate health and safety legislation, company codes of practice and local rules. Promote a culture of safety and compliance among reports and colleagues. Involve in various  site related activities.

What the role is:

The mission of SFA is to ensure and secure a supply of safe food for Singapore. The National Centre for Food Science (NCFS) supports SFA’s vision of ensuring safe food for all by being a national reference laboratory on food science, conducting food safety monitoring to generate scientific data for risk assessment and enforcement of food regulations to protect consumer health. NCFS oversees the application of science and technology to enable an evidence-based approach for ensuring food safety in partnership with stakeholders across the entire food chain and research institutions to address emerging food safety and security concerns.

You will be part of a dynamic team of Food Science Rapid Response Department (FSRRD) to provide support to SFA food safety monitoring and surveillance programs. The specialist teams of FSRRD strive to continue develop our testing capabilities and scientific knowledge to keep pace with the challenges of emerging food borne hazards in food. We collaborate with internal and external stakeholders to enhance food safety standards, support food security initiatives such as high-tech farming and evaluation of novel foods.

You will join us on an exciting journey to build the bioanalytical platform in NCFS to support the food safety regulatory control and the related R&D projects using cutting edge analytical technologies.

What you will be working on:

• Propose mid-term workplan for developing and expanding the bioanalytical capabilities of NCFS, in particular in the areas of proteins and polypeptides of food safety relevance based on various advanced mass spectrometry techniques.

• Develop new screening and targeted analytical methods for the identification of proteins, polypeptides and other biomacromolecules of potential adverse health effects in novel food and novel food processing technologies to support SFA toxicological study, food safety monitoring and surveillance programs.

• Prepare manuscripts for scientific publication in peer-reviewed journals and deliver presentation in international conferences.

• Contribute to inter-divisional taskforce for conducting scientific evaluation of novel agricultural technologies and novel food.

• Participate in collaboration projects with National and International partners on development and enhancement of testing capabilities.

• Implement laboratory quality assurance programmes to ensure that the laboratory practices are in full compliances with ISO/IEC 17025:2017 standard.

• Prepare regular reports to update management on the progress of research projects and significant test findings with robust risk assessments.

• Procurement of lab supplies and equipment to support the operation of the lab.

Overview of the role

The individual in this position is responsible for managing the company’s relationship with its customers. Account manager (MS) may be responsible for finding new business, be assigned prospects, given accounts or a combination thereof.

The candidate will be responsible for selling our high-end GC/MS and LC/MS instrumentation (Triple Quad) as well as other Mass-Spec related products.

• Achieve revenue targets via maintaining current accounts and developing new business opportunities.

• Visiting customers to build, develop and strengthen relationships.

• Forecasts and tracks client account metrics.

• Identifies opportunities to grow business with existing clients.

• Coordinate with staff members working on the same account to ensure consistent service.

• Prepares quotations for tender submissions based on tender specifications from various sales leads including the Singapore government procurement portal, GeBiz, Sesami, Ariba, etc.

• This is a local position and the applicant must be already residing in Singapore.

Overview of role

Keen to consider this unique opportunity to create the future for our leading brands?

Procter & Gamble’s Singapore Innovation Center (SGIC) is looking for a candidate who has strong technical background & experience in LC-MS!

The ideal candidate will develop and deploy mass spectrometric method to drive technology and product development across all business areas. You will join a multi-technique/discipline laboratory where both teamwork and individual initiative are highly valued. If this sounds exciting to you, read on!

Your team

Located at SGIC, you will be part of the Corporate Function, Analytical organization. You will work in multi-functional innovation teams. The group forms active partnerships with technology and product development to support a broad range of initiatives throughout our company.

How success looks like

• Establish the high-end LC-MS and Biomarker capability

• Lead innovations via the mass spectrometric methods to drive technology and product development across all business areas

Key Responsibilities

• Partner effectively with multi-functional, multi-disciplinary teams (e. g. upstream technology/product development and downstream go-to-market communications) and deliver critical mass spectrometry (MS) and biomarker needs

• Identify, develop, and deploy MS and Ligand Binding Assay (LBA) applications to the business via P&G internal and external connections

• Manage projects that may require analytical capabilities other than MS and biomarker analysis

Secondment Program: GC/LC-MS Analysis for Beauty Care Applications

Work Scope & Responsibilities:

· Leverage existing GC-MS and LC-MS tools and develop capabilities as needed for holistic understanding of interactions between ingredients in formulations

· Partner with multifunctional team in designing experiments for technology screening, MOA elucidation, and validating/building computational methods.

· The focus will be developing foundational understanding (molecular -to- macrolevel) of material interactions in formulations (complex systems)